Emizimbeni yabantu,icollagenibaluleke njengentliziyo esemzimbeni wethu.Isinceda sihlale siselula kwaye sisempilweni.Xa sizalwa, i-collagen iphezulu, kodwa njengoko sikhula, ukusilela kwe-collagen kwenzeka, kwaye sikhula.Nangona kunjalo, ukuguga kunokuthotywa ngokuthatha izongezo ze-collagen.Kodwa ingxaki apha kukho iindidi ezingama-28 zeCollagen emzimbeni wethu, kwaye kubaluleke kakhulu ukuba siqonde ukuba loluphi uhlobo esenza ntoni ukuze singagqithisi ngaphezulu kolunye uhlobo.Ngoko ke, qhubeka ufunda ukuze uzigcine umncinci kwaye usempilweni.
Umfanekiso-no-1-Iintlobo-ze-Collagen
➔ Uluhlu lokukhangela
1.Yintoni iCollagen?
2.Isebenza njani iCollagen eMzimbeni?
3.Iintlobo ngeentlobo zeCollagen: Zeziphi Iintlobo ezahlukeneyo?
Kanye njengokuba iinwele zethu zikhula ngokwemvelo, iCollagen yiproteni eyenziwa ngumzimba wethu rhoqo.
Umzobo akukho 2-yintoni-i-collagen
Kuyamangalisa ukuqaphela ukuba emzimbeni womntu, malunga ne-30% yeprotheyini ye-Collagen, kwaye xa kuthelekiswa nobunzima bomzimba wonke, iiprotheni zenza i-14 ~ 16%.I-Collagen ikhona kuyo yonke indawo, kanye njengomoya eMhlabeni;umzekelo, ungayifumana kumalungu, amathumbu, amathambo, ulusu, kunye nawo onke amanye amalungu omzimba womntu.
2) I-Collagen yenza ntoni emzimbeni?
Ezi zilandelayo ziindima zeCollagen emzimbeni wethu:
Umfanekiso we-3 Yintoni indima ye-collagen emzimbeni.
✓Ngaphakathi kwesikhumba -igcina ithambile, ilastiki, yomelele, kwaye ingenamibimbi.
✓Umaleko ophezulu kumalungu kunye namathumbu - sebenza njengomaleko okhuselayo
✓Ngaphakathi emathanjeni - inceda ekwakhiweni kwamathambo, kwandisa ukuxinana, kwaye ibambezela i-osteoporosis
✓Kumalungu - inceda ekubunjweni kwazo xa zisebenza njengeendawo zokuncamathela kunye nezinto ezifunxa ukothuka
✓Izikhonkwane -I-Collagen yenza i-keratin, ethi emva koko yenze izikhonkwane.Ke, iCollagen inoxanduva lokukhula kwezipikili kunye nempilo
✓Iinwele -Iprotein yokuqala, ikeratin, kwizinwele, ivela kwi-amino acid ethile ye-Collagen, ngoko ke, i-Collagen yenza iinwele.Ngaphezu koko, i-dermis layer, apho iifollicle zeenwele (iingcambu) zikhona, ubukhulu becala zenziwe ngeCollagen.
✓Ivazi yegazi -Iifibers ze-collagen zikhona ngaphantsi komgangatho wangaphakathi wemithambo yegazi ngendlela yothungelwano.Ngaphezu koko, babonelela ngenkxaso yesakhiwo, kwaye ngexesha lokwenzakala, basebenza njengemagnethi yeearhente zokuphilisa kunye nokunceda ukulungisa.
✓Phakathi kwemigca yezihlunu -zisebenze njengeglu kwizihlunu, zihlale zibotshelelwe kunye kwaye zinike ukunwebeka kwezicubu.Ziphinde zisebenze njengento ephakathi ukuhambisa amandla e-contractile ukusuka kwimisipha ukuya kwi-skeleton (amathambo, i-tendon, i-ligaments).
3) Zeziphi iintlobo ezahlukeneyo zeCollagen?
Umfanekiso we-4-Ziziphi-iintlobo-ezahlukeneyo-ze-Collagen
Izazinzulu ziye zafumanisa ngaphezulu kwe 28 iintloboCollagenyaye ahlelwa ngokusekelwe kwizinto zokwakha, ulungelelwaniso lwesakhiwo, kunye nemisebenzi ayenzayo.
Kwezi ntlobo zingama-28, kukho ii-Collagens ezi-5 ezineempembelelo ezininzi, ezinje;
a) Uhlobo lweCollagen I(ininzi kakhulu)
b) Uhlobo lweCollagen II
c) Uhlobo lweCollagen III(ininzi kakhulu)
d) Uhlobo lweCollagen V
e) Uhlobo lweCollagen X
a) Uhlobo I-Collagen kunye nosetyenziso lwayo
“I-Type I Collagen yiproteni ende, ene-triple-helical, kwaye yenziwe ngee-amino acids ezintathu: i-glycine, iproline, kunye ne-hydroxyproline.Iintsalela ze-glycine zenza undoqo we-triple helix, ngelixa iintsalela zeproline kunye ne-hydroxyproline zibonelela ngokuguquguquka kunye namandla.
Unokuqikelela ukubaluleka kohlobo lwe-Collagen ukusuka kwindawo ye-1 kwisigaba samagama ngenxa yokuba iqukethe i-90% yazo zonke i-Collagen emzimbeni womntu, ngokukodwa kwesikhumba, amathambo, kunye nezicubu ezidibeneyo (i-tendon, ligaments, cartilage).
➔ Ukusetyenziswa kohlobo I-Collagen
Njengoko Uhlobo lwe-Collagen luninzi kwesikhumba kunye namathambo, unokuqikelela ukuba umsebenzi walo oyintloko kukugcina ulusu luncinci kunye nokugcina amandla amathambo - iinkcukacha zazo zinikwe ngezantsi;
✓Impilo yesikhumba:Ukuba unemibimbi, uburhabaxa, okanye uburhabaxa eluswini lwakho, ke eyona ngxaki inkulu kukunqongophala kohlobo lwe-Collagen.
✓Ukufinyela kwezihlunu: Uhlobo I-Collagen nayo ibalulekile kwi-contraction ye-muscle.Inceda ukudibanisa imicu yezihlunu kwaye ivumela ukuba yenze isivumelwano kwaye iphumle.
✓Ukumila kwemithambo yegazi:Uhlobo I-Collagen nayo ibalulekile ekwenzeni imithambo yegazi.Inceda ukwenza iindonga zemithambo yegazi kwaye igcine yomelele kwaye isempilweni.
✓Ukuphiliswa kwenxeba:Uhlobo I-Collagen nayo ibalulekile ekunyangeni kwenxeba.Inceda ukwenza ukhwekhwe phezu kwenxeba kwaye inika isakhelo sokukhula kwezicubu ezintsha.
✓Ukulungiswa kweNqwela:Amalungu asemzimbeni womntu enziwe ngento ebambekayo ebizwa ngokuba yicartilage, kwaye le rhalaxa yenziwe ikakhulu ngoType I Collagen.ICartilage isebenza njengento yokutsala ukothuka kunye nendawo yokunciphisa ukukhuhlana phakathi kwamathambo amabini.
✓Ukwakheka kwamathambo:Ngaphandle kwamathambo, sifana nelaphu elide elibekwe phantsi.Umzimba wethu uvelisa amathambo ubukhulu becala kuhlobo lwe-collagen ye-I.Ke, ngakumbi Uhlobo lwe-Collagen luthetha ukuveliswa kwamathambo okungcono, ukuphiliswa ngokukhawuleza, kunye nesakhiwo samathambo esomeleleyo.
b) Uhlobo II Collagen & Usetyenziso lwayo
“Uhlobo lwe-II Collagen lwenziwe ngamatyathanga amathathu amade ee-amino acids adityaniswayo ukuze enze i-triple helix.I-helix kathathu ibonelela ngodidi lwe-II Collagen amandla kunye nokuguquguquka. "
Ikhoyo ininzi kakhulu kwi-cartilage edibeneyo kwaye inoxanduva lokuhambisa ukomelela kunye nokuguquguquka.Uhlobo II izongezo zeCollagen ziqhele ukwenziwa kwinkukhu okanye kwinyama yenkomo.
➔ Ukusetyenziswa koHlobo lwe-II Collagen
✓Impilo edibeneyo:Uhlobo lwe-II Collagen luninzi kakhulu kwi-cartilage, ngoko kuyavakala ukuba ukuthatha izongezo zayo kuya kunceda ukunyanga izifo zethambo & ezidibeneyo ezifana ne-osteoarthritis, njl.
✓Impilo yolusu:Olunye uphando lubonise ukuba uhlobo lwe-II Izongezo ze-Collagen zinokunciphisa ukubonakala kwemibimbi kunye namabala eminyaka kwaye zincede ukuphucula ukunyameka kwesikhumba.
✓Impilo yamathumbu:Olunye uphando lophando lubonise ukuba uhlobo lwe-II Izongezo ze-Collagen zinokunceda ukukhusela indawo yangaphakathi / yangaphandle yamathumbu kunye nokuphucula ukugaya kunye nokufunxa izondlo.
✓Umsebenzi wenkqubo yamajoni omzimba:Uhlobo II izongezo zeCollagen zikwasetyenziswa ngamanye amaxesha ukunceda amajoni omzimba ukulwa nezifo, nto leyo ekhokelela ekuchacheni ngokukhawuleza kwizifo.
c) Uhlobo lwe-III Collagen kunye nosetyenziso lwayo
“Ngokwesakhiwo, Uhlobo IIICollagenyenziwe ngamatyathanga amathathu afanayo ealpha, iyenza ihomotrimer, ngokungafaniyo noHlobo I Collagen, olunamatyathanga amabini ealpha1 kunye netyathanga lealpha2 elinye.”
Xa kuziwa kuHlobo lwe-III i-collagen, ludidi lwe-2 luninzi lwe-Collagen kumzimba womntu.Isasazwa ngokubanzi kuzo zonke izihlunu ezahlukeneyo ezifana nezibilini, imithambo yegazi, isibeleko, ulusu, kunye neenwebu zamalungu.Ngokutsho kwedatha evela kwiindawo ezahlukeneyo zomzimba womntu, irekhodwa Uhlobo lwe-I ukuya kwi-III Collagen ratio ifana ne-4: 1 ( ulusu ), 3: 1 ( izitho ), njl.
Olu hlobo lwe-Collagen, olubizwa ngokuba yi-fibrillar, ludala imicu emide, encinci enika izicubu ezinamandla kunye nokuguquguquka.Ngaphezu koko, ikwanceda amanxeba aphole ngokukhawuleza.Ukongezelela, igcina i-architecture yemithambo yegazi kunye namanye amalungu, inceda ukusebenza kwayo ngokufanelekileyo.
➔ Ukusetyenziswa koHlobo lwe-II Collagen
✓Impilo edibeneyo:Uhlobo lwe-III I-Collagen ayikho into eninzi kumathambo kunye ne-cartilage, kodwa ikhona kwaye inceda ukuxhasa ezinye iintlobo ze-cartilage ukugcina amandla ethambo kunye nempilo.
✓Impilo yolusu:Uhlobo lwe-III I-Collagen ininzi kakhulu eluswini, njenge-Type I Collagen, kwaye inceda ulusu ukuba luphephe imigca emihle, ethi kamva ibe yimibimbi.Kwaye, Uhlobo lwe-III Collagen lubumba inethiwekhi yolwakhiwo phantsi kolusu ukugcina ulusu luqinile, kodwa njengoko iCollagen i-elastic, ulusu luhlala lunwebeka.
✓Impilo yeenwele: I-Tpye III Collagen ibonelela ngezinto eziluhlaza zokubunjwa kweenwele, ngoko ke iphakamisa ukukhula kweenwele kunye namandla.Ngaphezu koko, i-protein ye-Type III nayo ifumaneka kwi-scalp apho iingcambu zeenwele zikhona.Ngamafutshane, ukuthatha i-Type III Collagen supplements kuya kunceda umntu oneenwele ezibuthathaka.
✓Ukuphiliswa kwenxeba:Uhlobo lwe-III luyiprotheni ye-Collagen yesibini kwimisipha kunye namalungu, kwaye njengoko uyazi, i-Collagen yimagnethi yendalo yokuphilisa iiseli;kwimeko yokulimala, i-Collagen inceda ukwenza izicubu ezitsha ngokukhawuleza.
✓Ukungakhuseleki:Uhlobo lwe-III Collagen lunokunceda ekutyebiseni ukhuseleko ngokukhupha ukuveliswa kweeseli ezimhlophe zegazi.Ihlala isetyenziselwa izongezelelo zokunyanga izifo ezizimelayo kunye nezinye izifo ze-immune system.
d) Uhlobo lwe-V Collagen kunye nosetyenziso lwayo
"Olu hlobo lwe-Collagen luhlelwa njenge-fibrillar, luthungelwa kwiintsinga ezinde, ezifana nentambo ezinikezela amandla kunye nokuguquguquka kwezicubu-zisebenza noHlobo loku-I kunye noHlobo lwe-III Collagens, idala i-scaffolding yezicubu kunye namalungu."
Uhlobo lwe-V Collagen aluninzi njengezinye iintlobo ezintlanu ezinkulu ze-Collagen, kodwa lwenza imisebenzi ebalulekileyo efana nokwenza ujiko lwamehlo, umaleko wolusu kunye neenwele, kunye nezicubu ze-placenta.Ukusebenza ngaphakathi kwe-matrix ye-extracellular yezicubu ezahlukeneyo, ezinje ngolusu, amathambo, imithambo yegazi kunye ne-placenta, ibonelela ngenkxaso ebalulekileyo yesakhiwo.
➔ Ukusetyenziswa koHlobo lwe-II Collagen
✓Iinwele kunye neenzipho:Ixhasa impilo kunye nokomelela kweenwele kunye nezinzipho.
✓Impilo yamehlo:Liyinxalenye ephambili ye-cornea, igalelo ekugcineni imilo yeliso kunye nokucaca.
✓Ukomelela kolusu:Uhlobo lwe-V Collagen lunceda ekugcineni impilo yolusu, igalelo kumandla alo kunye nokuqina.
✓Ivazi yegazi: Uhlobo lwe-V I-Collagen yakha isakhiwo seendonga zemithambo yegazi, igalelo ekuzinzeni kwabo kunye nomsebenzi ofanelekileyo.
✓Ulwakhiwo lwezicubu: Uhlobo lwe-collagen lwe-V lunceda ezinye iintlobo ze-collagen ekwenzeni izicubu ezahlukeneyo kunye ne-organ layers, ngoko inceda ekukhuleni kwabo okunempilo.
e) Uhlobo X Collagen & Usetyenziso lwayo
"Uhlobo lwe-X Collagen lubandakanya i-helix emfutshane kathathu ye-Collagen ejikelezwe yimimandla emibini engeyiyo i-collagenous, i-NC2 kunye ne-NC1."
Inceda ekubopheleleni iiminerali ezibalulekileyo, ezifana nekhalsiyam, kwimicu yeCollagen, yomeleza amandla ethambo-ngokwenza oko, inegalelo ekomeleleni kwenkqubo yethu yamathambo.
Ngokungafaniyo nezinye iintlobo ze-Collagen, ayenzi imicu emide kodwa yenza inethiwekhi yeentsinga ezimfutshane.Le nethiwekhi ecacileyo inika amandla kunye nokuguquguquka kwiplani yokukhula kunye nommandla obaliweyo we-articular cartilage.
➔ Ukusetyenziswa koHlobo lwe-II Collagen
Oku kulandelayo kukusetyenziswa kohlobo X lweCollagen;
✓Indima ekhethekileyo:Nangona ifunyenwe kwixabiso elincinci, umsebenzi wayo owahlukileyo kuphuhliso lwamathambo uqaqambisa ukubaluleka kwayo.
✓Umbonakalisi woTshintsho:Uhlobo lwe-X Collagen lusebenza njengommakishi ngexesha lokuphuhliswa kwamathambo, ebonisa ukutshintshwa kwi-cartilage ukuya kwithambo eliqinileyo.
✓Isalathisi sePlayithi yokuKhula:Ubukho bayo kwiipleyiti zokukhula bubonisa utshintsho olubalulekileyo oluxhasa ukukhula kwamathambo amade.
✓Umququzeleli woHlumo:Ngokuncedisa olu tshintsho, Uhlobo lwe-X Collagen luqinisekisa ukuba amathambo akhula kokubili ubude kunye namandla, ayimfuneko kwimpilo yamathambo eqinile kunye nokunyaniseka kwesakhiwo.
➔ Isiphelo
Abavelisi beCollagenemhlabeni jikelele yenza izongezo ezikhethekileyo ezijolise ekuveliseni uhlobo oluthile lweCollagen, njengoHlobo lwe-I okanye uhlobo lwe-II kunye nabanye.Nangona kunjalo, kubalulekile ukuqaphela ukuba ezinye zinjalobovine Collagen abavelisi, ezinye ziyingulube, ngelixa ezinye zisebenzisa iindawo zezilwanyana ezixubeneyo - ezinokuthi zibe yingxaki kumgangatho kunye namasiko athile ( ingulube i-Collagen i-haram kwi-Islam).
Nangona kunjalo, thina kwaYasin sijonge ukwenza iCollagen kuzo zonke iintlobo zezilwanyana kodwa kwizikhongozeli ezithile ukuqinisekisa ukuba abathengi bayayifumana le nto bayifunayo.Ke, ukuba ungowabathengisi beeprotheyini okanye ababoneleli ngomgubo weCollagen, sinokuqinisekisa ukuba ufumana i-100% yeemveliso eziyinyani kuthi.
Ixesha lokuposa: Sep-08-2023